Latex Medical Gloves: Time for a Reappraisal
Many hospitals have implemented policies to restrict or ban the use of devices made of natural rubber latex (NRL) in healthcare as precautionary measures against the perceived risk of NRL allergy. Changes in glove technology, progress in measuring the specific allergenic potential of gloves and a dramatic decrease in the prevalence of NRL allergies after interventions and education prompted us to revisit the basis for justifiable glove selection policies. The published Anglophone literature from 1990 to 2010 was reviewed for original articles and reviews dealing with the barrier and performance properties of NRL and synthetic gloves and the role of glove powder. The review shows that NRL medical gloves, when compared with synthetic gloves, tend to be stronger, more flexible and better accepted by clinicians. The introduction of powder-free gloves has been associated with reductions in protein content and associated allergies. Recently, new methods to quantify clinically relevant NRL allergens have enabled the identification of gloves with low allergenic potential. The use of low-protein, low-allergenic, powder-free gloves is associated with a significant decrease in the prevalence of type I allergic reactions to NRL among healthcare workers. Given the excellent barrier properties and operating characteristics, dramatically reduced incidences of allergic reactions, availability of specific tests for selection of low-allergen gloves, competitive costs and low environmental impact, the use of NRL gloves within the hospital environment warrants reappraisal.
In recent years, many hospitals and health care settings around the world have decided to restrict the use or totally ban all natural rubber latex (NRL) devices as precautionary measures to NRL allergy threats. As is widely acknowledged, type I or IgE-mediated NRL allergy has, for several years, been one of the most significant occupational health problems [for reviews, see [1,2,3]]. However, it is now also acknowledged that new cases of NRL allergy have reduced significantly and sometimes virtually disappeared in countries and hospital regions where health authorities have required the use of low-allergen/low-protein, non-powdered protective medical gloves. Thus, policies which ban the use of NRL devices may be an overreaction that can lead to unexpected compromises in the primary purpose of using protective gloves, that is, providing a competent barrier to protect against infections for both healthcare professionals and the patients [4,5]. These controversies prompted us to revisit the basis for justifiable glove selection policies.
As is well known, NRL has been used as a material for the production of gloves for almost a century. Throughout the 1990s there were increasing concerns about transmittable diseases, particularly HIV infection and hepatitis, which resulted in a dramatic increase in the use of NRL gloves. Escalating glove use in the 1990s was associated with the rise in reports of allergic reactions to NRL gloves among healthcare workers [1,6,7,8,9,10]. The increased demand for gloves led to an upsurge in glove production, especially in Malaysia. Between 1987 and 1989 the Malaysian Rubber Development Board received over 400 applications to form glove companies where previously only 25 existed [11]. Early on in the history of NRL allergy, some authors [12,13] suggested that the increased production in response to the sudden upsurge for latex gloves often led to inadequate leaching to reduce protein levels.
The healthcare community requires medical gloves, both for examination and surgery, in order to provide a barrier that prevents transmission of micro-organisms to and from patients [4]. Many factors are involved in the choice of materials for the production of medical gloves, which relate to both the protective effect as well as ease and comfort of use [14,15]. For a large number of healthcare practitioners, NRL continues to be the glove material of choice [15,16].